How to make and pay for ordering of Danazol capsules online?

You can order the delivery of Danazol capsules in any of three ways:

1.on the website of the pharmacy;

2. via a smartphone app (if available);

3. by phone.

There is no minimum order amount.

You can pay for the order of Danazol capsules immediately on the website (in the application) or later to the courier - in cash or by credit card. Any order can be canceled until the moment of payment. But in this case, you still need to pay for the delivery service.

When buying, the seller is obliged to inform the buyer:

1. about the indications for the use of the drug;

2. about its price;

3. about the expiration date;

4. about the terms of sale;

5. about the storage rules;

6. about interactions with other medications.

This information should be announced when ordering by phone, placed in the description on the website and in the application.

If the buyer wants, he can ask the pharmacy to provide documents confirming the quality of the Danazol drug.

How to get an order?

Just like any other drug. Upon receipt of the order, you need to check the integrity of the package, the presence of damage and the proper type of the drug (if possible). If everything is fine, then you need to sign for the receipt and confirm the absence of claims to the pharmacy or delivery service.

Medicines are delivered in sealed packaging. If the order contains several drugs with different storage modes, then they are packed separately. Preparations that require storage at low temperatures are delivered in special bags or containers, where the required temperature is maintained and there is an electronic thermometer. You can even ask the courier to show you the storage temperature during transit.

If the buyer is not at home, then his relatives can get medicines for him. But for this they need to show documents that will confirm the payment or order. This can be, for example, an electronic check, a copy of the order confirmation letter that usually comes by e-mail, a screenshot of the order screen.

Description of the active components of the drug Danazol.

The scientific information provided is generalized and cannot be used to make a decision on the possibility of using a particular medicinal product.

Marketing Authorization Holder:

REMEDICA, Ltd. (Cyprus).

ATX code: G03XA01 (Danazol).

Active ingredient: danazol.

Dosage form:

Danazol Capsules.

Release form, packaging and composition of the drug Danazol:

Danazol capsules: 50mg, 100mg and 200mg.

Clinical and pharmacological group:

Inhibitor of gonadotropin production.

Pharmaco-therapeutic group:

Gonadotropin-releasing hormone inhibitor.

Pharmachologic effect

An inhibitor of the production of gonadotropic hormones. Causes reversible suppression of LH and FSH production by the pituitary gland in men and women. Does not possess estrogenic and gestagenic activity. Has a weak androgenic activity with a concomitant anabolic effect.

Suppresses proliferation and causes atrophy of normal and ectopic endometrial tissue.

Reduces the loss of menstrual blood, the mechanism of this action has not been completely established.

Inhibits ovulation and reduces plasma levels of 17-estradiol. It remains unclear whether the inhibition of endometrial proliferation is due to a decrease in estradiol levels or a direct effect of danazol on endometrial estrogen receptors.

After discontinuation of danazol, ovulation usually resumes within 5 weeks, which is accompanied by a characteristic sharp increase in LH and a slight increase in FSH.

Pharmacokinetics.

After oral administration, danazol is absorbed from the gastrointestinal tract. Absorption increases with simultaneous food intake. It is metabolized in the liver, the main metabolite is 2-hydroxymethyltestosterone. T1 / 2 is about 4.5 hours.

Indications of the active substances of the drug Danazol.

Endometriosis with concomitant infertility, benign breast neoplasms (fibrocystic breast disease), primary menorrhagias, premenstrual syndrome, gynecomastia; hereditary angioedema.

Dosage regimen.

The method of application and dosage regimen of a particular drug depends on its form of release and other factors. The optimal dosage regimen is determined by the doctor. It is necessary to strictly observe the compliance of the used dosage form of a particular drug with the indications for use and the dosage regimen.

Dose, frequency of administration and duration of treatment are determined individually. The maximum dose for adults is 800 mg / day. As a rule, danazol is used in the lowest effective dose.

Side effect

From the endocrine system: amenorrhea, flushing of the face, increased sweating, a decrease in the size of the mammary glands, changes in libido, vaginitis, emotional lability, nervousness, acne, increased secretion of the sebaceous glands, slight hirsutism, edema, weight gain, coarsening of the voice, androgenic alopecia, disorders of spermatogenesis.

From the digestive system: dysfunction of the gastrointestinal tract, an increase in the activity of liver enzymes; rarely cholestatic jaundice.

From the side of the central nervous system: headache, dizziness, tremors, depression, weakness, sleep disturbances are possible; rarely - a slight increase in intracranial pressure.

On the part of the hematopoietic system: an increase or decrease in the number of blood cells.

Dermatological reactions: skin rash.

From the side of metabolism: hyperglucagonemia, impaired glucose tolerance, an increase in serum LDL cholesterol concentration, a decrease in serum HDL cholesterol concentration.

From the side of the cardiovascular system: rarely - tachycardia, arterial hypertension.

Others: back pain, muscle cramps or cramps; rarely - visual impairment.

Contraindications for use.

Severe violations of liver and / or kidney function, chronic heart failure, porphyria, thromboembolic disorders (including in history), androgen-dependent tumors, vaginal bleeding of unknown origin, breast cancer, carcinoma, pregnancy, lactation period, hypersensitivity to danazol.

Application during pregnancy and lactation.

Contraindicated during pregnancy and lactation.

In women of childbearing age, it is necessary to exclude pregnancy before using danazol; it is recommended to start treatment with danazol on the first day of menstruation. In patients with amenorrhea, a pregnancy test should be performed before starting therapy.

The use of high doses of Danazol prevents ovulation. However, ovulation is possible at low doses, so non-hormonal methods of contraception should be used during danazol treatment.

Application for violations of liver function.

Danazol is used with caution in patients with liver disease.

The use of Danazol for impaired renal function.

The drug is used with caution in patients with kidney disease.

Application in children.

Danazol is not recommended for children.

Use in elderly patients.

It is not recommended to use Danazol in elderly patients.

Special instructions.

Danazol is used with caution in patients with liver disease, kidney disease, arterial hypertension and other cardiovascular diseases, in conditions that can be exacerbated by fluid retention (including diabetes mellitus, epilepsy, polycythemia, lipid metabolism disorders), with migraine, violation of plasma hemostasis mechanisms;

Danazol is used with caution in patients with a previous androgenic response to sex hormone treatment.

When using the drug in patients with diabetes mellitus, a dose adjustment of insulin is required.

Danazol affects some laboratory indicators of sex hormones (for example, increases testosterone levels).

It is not recommended to use danazol in elderly patients.

It can be used in children with premature puberty.

Drug interactions.

Danazol enhances the effect of coumarin anticoagulants and indandione derivatives (the risk of bleeding increases).

Capsules weaken the effect of insulin and oral hypoglycemic drugs (affecting carbohydrate metabolism, increases the concentration of glucose in the blood).

Danazol increases the concentration of glucagon in the blood plasma.

Danazol may decrease the effectiveness of antihypertensive drugs, possibly by increasing fluid retention in the body.

Danazol inhibits the metabolism of antiepileptic drugs (carbamazepine, phenytoin and phenobarbital) and increases their concentration in the blood.

The drug increases the plasma concentration of cyclosporine and tacrolimus (the risk of nephrotoxicity increases).

Danazol is capable of causing hypercalcemia with the use of alfacalcidol in primary hypoparathyroidism.

Method of administration and dosage.

The capsules are taken orally with a small amount of water. The drug must be taken on the first day of the menstrual cycle. The initial dose of Danazol for endometriosis is 400 mg per day, with a further increase to 800 mg. The duration of therapy is 6 months.

For preoperative preparation, 1-2 months before the operation, patients take 300-400 mg of the drug per day. For the treatment of menorrhagia and premenstrual syndrome, take 100-400 mg of Danazol per day for 3 months, and in cases of mastopathy - 300 mg per day for 3-6 months.

To prevent angioedema, 200 mg of the drug is prescribed per day, then the dose is gradually reduced in the absence of exacerbations. The course of treatment varies within 30-90 days.

Children with premature puberty take 100 to 400 mg of the drug per day. The duration of therapy is determined by the doctor on an individual basis.

Features of the use of Danazol capsules.

All patients taking Danazol should undergo regular liver function tests. If the course of treatment lasts 6 or more months, it is necessary to conduct an ultrasound of the liver and pelvic organs.

When treating patients with diabetes mellitus, it is necessary to adjust the dosage of insulin.

High doses of the drug can prevent ovulation. Small dosages of Danazol do not always affect ovulation, so in this case, you need to take care of non-hormonal contraception.

Patients with diabetes mellitus who are undergoing Danazol therapy have to adjust the insulin dose. An increased dose of the active ingredient may temporarily stop ovulation.

Danol (Danazol) is taken orally in doses prescribed by your doctor.

The standard dosage for adults is 200-800 mg per day, divided into two to four doses.

The minimum dose for genital endometriosis is 400 mg per day. Depending on the effect, the dosage is adjusted. The course of therapy is 4 to 6 months.

During the treatment of benign breast masses, 100 to 400 mg per day are prescribed.

With pronounced premenstrual syndrome and heavy bleeding during menstruation, the drug is taken in an amount of 200 mg for three months.

What is the price of Danazol capsules? Where is it profitable to buy the drug online?

The price of an effective hormonal drug on our website (banner at the top of the page) is much lower than in other pharmaceutical companies. Would you like to buy an original medication as soon as possible? Call us by phone, follow the "Buy" link, or order a call back.

1. The price of a medicine may vary slightly depending on the manufacturer, the exact price is specified by telephone by our employees.

2. You can buy Danazol right now, the medicine is always available.

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